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Carboxylesterase 2 prevents liver steatosis by modulating lipolysis, endoplasmic reticulum stress, and lipogenesis and is regulated by hepatocyte nuclear factor 4 alpha in mice
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2021;86:e654e660
L.ViaJ
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To determine if P-gp expression levels predicts the degree of collateral sensitivity to tamoxifen, and the role of P-gp ATPase activity, two drug resistant cell lines (e.g., CHO R C5 and MDA-Doxo 400 ) expressing different levels of P-gp were allowed to proliferate in the presence of increasing concentrations of tamoxifen, without or with specific inhibitor of P-gp-ATPase activity (PSC-833 [33];)
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